What to watch for during preseason action on Thursday in the Houston Astrodome.

The Texans host the Kansas City 49ers on Thursday night.

The game is expected to be one of the most anticipated in franchise history.

The teams will face off for the second time in three years.

The Texans are coming off a 30-10 loss to the Carolina Panthers in Week 1.

The Chiefs will be coming off an 18-10 win over the San Diego Chargers on Saturday.

The matchup could be a key one for both teams.

Both teams have played in preseason games the past two years.

Houston will be facing off against a new-look defense.

Kansas City is coming off its first loss of the season, a 24-10 defeat at home to the New Orleans Saints.

The Chiefs won their second preseason game against the Tennessee Titans, 27-17.

The Kansas City defense is led by Pro Bowl linebacker Justin Houston and Pro Bowl cornerback Marcus Peters.

The duo combined for six interceptions and a sack against the Saints.

Houston is in his first season as a starter and will be asked to play in the Chiefs’ first preseason game since 2013.

The rookie is expected back after missing the first four games of the regular season with a shoulder injury.

The rookie is not expected to play.

Pro Bowl safety T.J. Ward will start at corner for Kansas City.

Ward is a Pro Bowl selection.

He played in 12 games last season with nine starts.

Kansas, which has already lost four starters, needs Ward to step up.

The team has also struggled in the run game this preseason.

The team is expected run the ball just 14.7 percent of the time this season.

The second-ranked rushing attack in the NFL is averaging just 13.1 yards per carry.

The NFL season is just over a week away.

The teams play Thursday at 7:30 p.m.

CT on ESPN and on Fox in the United States.

Follow me on Twitter @Mike_Bennett

Tags: